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Current Lab Members

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Madhavee Thumiah, MSc Student

Madhavee earned her B.Sc. with Honours in Biotechnology from the University of Mauritius in 2014. She did her undergraduate thesis in Dr. Joyce Soulange's laboratory where she extracted and micropropagated Parsley leaves to analyze their phytoconstituents. After graduation, she worked as a Laboratory Research Engineer at CIDP Mauritius for two scientific laboratories, CIDP Preclinical Laboratory and CIDP Research and Innovation Laboratory. Her research involved selection, extraction, in vitro/in vivo testing and scientific valorization of natural ingredients. In 2019, she joined the Masters program of Cellular and Molecular Medicine at the University of Ottawa where she is conducting her research in Dr Mireille Khacho's and Dr. Yan Burelle's laboratories. Her graduate work focuses on the role of mitophagy in muscle stem cell fate during muscle regeneration.

Leah Susser, PhD Student

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Tina Podinic, Honours Student

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Jiaxuan Wang, Honours Student
Jessika Royea, Postdoctoral Fellow

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Steven Wade, MSc Student

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Nikita Larionov, Laboratory Technician

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Postdoctoral Fellows

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Dr Matthew Triolo, Postdoctoral Fellow

Prior to his time at the University of Ottawa, Matthew completed his BSc in Kinesiology and Health Science with a Minor in Biology at York University. After completing his MSc under the guidance of Dr. Michael Connor, studying whether electrical pulse stimulation can enhance muscle cell activity, he subsequently worked towards his PhD as a member of the Muscle Health Research Centre at York University. While under the supervision of Dr. David Hood his work focused on skeletal muscle autophagy, mitophagy and lysosome biogenesis in models of disuse, aging and exercise. As a Postdoctoral Fellow, Dr. Triolo is investigating mechanisms by which mitochondrial mediated signaling regulates muscle stem cell homeostasis and function. He enjoys playing a variety of sports including hockey, golf and baseball, and spending time with his family, friends, and cats.

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Dr Sidhanth Jayprakash Chirukandath, Postdoctoral Fellow

Sidhanth completed his PhD under the supervision of Dr. T.S. Ganesan from Cancer Institute (WIA) under the affiliation of University of Madras. His PhD research was studying the signaling by ErbB2 in ovarian cancer cells using a mass spectrometry-based approach. Afterwards, he did his postdoctoral research under the supervision of Professor Bruce G Allen at Montreal Heart institute. His postdoctoral research was studying the phosphorylation changes on stimulation of nuclear GPCRs in cardiac fibroblasts using mass spectrometry.  Apart from research, Sidhanth like playing and following sports like cricket and soccer.

Graduate Students

Steven Wade, PhD Candidate
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Steven completed his BSc in Neuroscience and Biology at Carleton University in his hometown of Ottawa. Previously, he worked under the supervision of Dr. Ken Storey where he completed his fourth-year thesis project examining the role of mRNA methylation in wood frog brain during hypoxia and whole-body freezing. Steven is completing his PhD in biochemistry where he is looking to uncover the signals regulated by mitochondrial dynamics that dictate nuclear gene expression to regulate muscle stem cell function. Outside of the lab, Steven enjoys playing the piano and trying new foods across Ottawa.

Kayla-Lynn Ferguson, PhD Candidate
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Kayla completed her BSc degree in Biopharmaceutical Science with a concentration in genomics at the University of Ottawa during which she won best 4th year honours project for her work exploring the structure and function of a mutant variant of the Sigma-1 Receptor underlying juvenile ALS. Under the supervision of Dr. Richard Bergeron, Kayla began her MSc Neuroscience thesis work investigating the Sigma-1 Receptor and its role in ER stress and autophagy, as well as characterizing several other mutant variants that underlie hereditary motor neuropathies. After transferring into the doctoral program, Kayla is currently completing her PhD in Neuroscience at the University of Ottawa under the supervision of Dr. Mireille Khacho where she is studying the role of the Sigma-1 Receptor in lipid metabolism.

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Olivia Sommers, TMM accelerated MSc student

Olivia is currently pursuing a BSc in Translational and Molecular Medicine and an accelerated MSc in Biochemistry. She is excited to work in the Khacho lab to characterize the effects of chronic OPA1 loss in muscle stem cell function and maintenance. Her interests lie primarily in mitochondria and the molecular basis of disease, and she has also had the opportunity to research bacteriophage biology. Outside of the lab, Olivia enjoys spending time with friends and reading.

Undergraduate Students

Soniya Agarwal, UROP student
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Soniya is a third-year undergraduate student studying Biomedical Science with a specialization in Cellular and Molecular Medicine. She previously completed her UROP project, which entailed the characterization of the role of the mitochondrial protein OPA1 in muscle stem ability to regenerate. Currently, she is looking into the effects of the OPA1 inhibitor drug on myoblast differentiation. She plans to continue research as her future career. Outside of the lab and school, she is a figure skater and a CanSkate coach. In her free time, she enjoys reading and playing the flute and violin.

Rholls Tomsine, Undergraduate Student
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Rholls is a 4th year undergraduate student studying Biochemistry with a specialization in Immunology and Microbiology. Having completed his UROP project during winter semester 2023. He later received the NSERC-URSA scholarship and is excited to put his skills to the test by working full-time during the summer. His work entails uncovering the effects of mitochondrial dynamics on nuclear gene expression. Rholls is fascinated with research involving aging, immunology and now mitochondria. He has plans to continue his education past an undergraduate degree, his dream being to eventually run his own lab. Outside the lab he volunteers with Connect Canadians, which aims to bring technology literacy to older adults across Canada. He also enjoys volleyball, frequenting the gym, videogames, occasionally reading and various movies and shows.

Staff

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Nikita Larionov, Lab Technician
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